Nanoscale clustering of RGD peptides at surfaces using comb polymers. 2. Surface segregation of comb polymers in polylactide.

Molecular Substrate Design for the Selective Adhesion, Proliferation and Differentiation of Marrow Connective Tissue Progenitors

A multi-faceted approach was applied to the molecular design of substrates for the selective adhesion, proliferation and differentiation of connective tissue progenitors (CTPs) from human bone marrow aspirates. The basic premise of the thesis is that integrin-specific adhesion peptides, when presented in a biophysically appropriate spatial arrangement against an inert background, allow enrichme...

Adsorption of comb copolymers on weakly attractive solid surfaces.

In this work continuum and lattice Monte Carlo simulation methods are used to study the adsorption of linear and comb polymers on flat surfaces. Selected polymer segments, located at the tips of the side chains in comb polymers or equally spaced along the linear polymers, are attracted to each other and to the surface via square-well potentials. The rest of the polymer segments are modeled as t...

Controlling cell adhesion on polyurethanes{

Cell attractive or non-attractive surface properties of polyurethane devices can be controlled by treating them with zirconium tetra(tert-butoxide). This gives reactive interfacial zirconium complex species that can be used subsequently to bond cell attractive peptides such as arg-gly-asp (RGD) or cell non-attractive organics such as polyethylene glycol (PEG) to the device surface. Control of t...

Comb-like Polymers inside Nanoscale Pores

Investigation of the ultrasonic welding strength in glass fiber reinforced thermoset polymers with surface preparation method using laser beam

In this research, tensile strength of ultrasonic welded parts made of thermoset polymer-reinforced glass fiber with surface preparation has been investiagted. In order to elevate the adhesion of two surfaces laser grooving method has been applied. Two type of thermoplastic materials including Plymethyl methacrylate (PMMA) and polypropylene (PP) have been used as interlayers. Influences of main ...